eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are prevalent
in fish and fish oils, have been studied in thousands of investigations. A
consistent body of evidence has been elaborated in various types of
investigations, ultimately demonstrating reduction in total mortality,
cardiovascular mortality, and morbidity by ingestion of roughly 1 g/d of EPA
plus DHA. …
A current theory proposes that a defect in methylation processes is central to
the biochemical basis of the neuropsychiatry of these vitamin deficiencies. …