Olanzapine long-acting injection is an investigational formulation that combines
olanzapine, an atypical antipsychotic, with pamoic acid resulting in a salt that
sustains the delivery of olanzapine for a period of up to four weeks.
Long-acting injectables have been associated with improved treatment for
patients who struggle with adherence to oral medications.(i) …
The lawsuit alleges that “Merck’s costly promotional campaign was intended to
convince purchasers that the drug was not only safe, but that they should demand
it from their healthcare professionals for pain treatment,” according to a
statement from the attorney general. …
Extensive clinical testing would be needed to draw conclusions about the safety
of TOFA and C75, or similar compounds, as antiviral treatment. That said, the
team took an early look at toxicity, exposing uninfected fibroblasts to C75 or
TOFA for 96 hours. They found that the drugs blocked HCMV replication without
causing cell toxicity or self-destruction (apoptosis). …
“Our results suggest the genetic make-up of patients could predispose their
responsiveness to a drug. This could have important implications for the future
of personalized molecular-based or individualized medicine,” …