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Hemp -Marijuana, Pharmacokinetics

New cannabis-like drugs could block pain without affecting brain, says study

“Our new study is very promising because it suggests that we could alleviate
pain by targeting the cannabinoid receptor CB2 without causing the kinds of
side-effects we associate with people using cannabis itself.”

…

September 15, 2008 by Hakeem Ali-Bocas Alexander3 Min Reading
Implications, NeuroPsyche, Toxicology

Atypicals no better than older meds in kids

That’s bad news for the companies that make leading atypicals–Johnson & Johnson Risperdal, Eli Lilly (Zyprexa), Bristol-Myers Squibb (Abilify),Pfizer (Geodon), AstraZeneca(Seroquel). Prescription rates for these meds have enjoyed a
strong growth curve, increasing more than fivefold among children over the past
15 years. …

September 15, 2008 by Hakeem Ali-Bocas Alexander2 Min Reading
Implications, Toxicology

State Sues Maker of Risperdal

The lawsuit was filed for the Attorney General’s Office in the 1st Judicial
District Court in Santa Fe by a Houston civil litigation firm, Bailey Perrin
Bailey, which specializes in lawsuits over the new generation of antipsychotic
drugs known as atypical antipsychotics. …

September 12, 2008 by Hakeem Ali-Bocas Alexander3 Min Reading
Pharmacogenetics

New genetic map used to advance drug research

“They are interested in pharmacogenetic purposes to do case control studies of
adverse drug reactions,” said John Novembre, a co-author of the study published
in Nature. …

September 9, 2008 by Hakeem Ali-Bocas Alexander1 Min Reading
Implications, Toxicology

Why do people love to hate pharma?

the public doesn’t trust pharma to share adverse info on their meds, further undermining that faith–and hurting
pharma’s rep. …

September 9, 2008 by Hakeem Ali-Bocas Alexander2 Min Reading
Implications, NeuroPsyche, Toxicology

Judge unseals secret Zyprexa papers

Eli Lilly will face a class-action suit over Zyprexa, now that a federal judge
has certified a group of insurance companies, pension funds, and unions that
want the drugmaker to repay them for the billions they spent on the
controversial antipsychotic drug. …

September 9, 2008 by Hakeem Ali-Bocas Alexander2 Min Reading
Hemp -Marijuana

Positive Sativex® Study Confirms Long Term Efficacy in MS Neuropathic Pain

Until now, all the evidence for long-term maintenance of efficacy of Sativex has
come from long-term open-label exposurei. The results reported today confirm in
the context of a placebo-controlled double-blind study that efficacy is indeed
maintained in long-term use. …

September 9, 2008 by Hakeem Ali-Bocas Alexander3 Min Reading
Implications, Toxicology

FDA names 20 drugs in safety probes

The FDA has already warned patients and docs about some of the drugs on the
first list of 20 under scrutiny, such as TNF
blockers
, in the news last week. …

September 8, 2008 by Hakeem Ali-Bocas Alexander2 Min Reading
Education, Implications

Free Drug Samples May End Up Costing Uninsured More

Researchers found that, for uninsured patients, the percentage of medications
prescribed as generics rose from 12 percent to 30 percent after the clinic
closed its drug sample closet. For Medicaid patients, however, there was no
significant change in generic prescribing. …

September 8, 2008 by Hakeem Ali-Bocas Alexander5 Min Reading
NeuroPsyche

Time to Effectiveness for Clozapine/clozaril

…The antipsychotic action may be secondary to other consequences in the brain
that evolve over a period of several weeks. …

September 7, 2008 by Hakeem Ali-Bocas Alexander1 Min Reading
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