Year: 2009

BioChemistry, Genetics, Toxicology

New paradigm identifies gene responsible for acetaminophen-induced liver injury (FierceBiotech)

In this study, a team of researchers led by Dr. David Threadgill of North
Carolina State University utilized mouse genetics to aid the search for
candidate genes linked to acetaminophen-induced liver injury in humans. “We
approached the study from the perspective that drugs are used in very
heterogeneous patient populations, and that drug-induced toxicities are likely
the result of a person’s genetic makeup,” …